Endocrine Abstracts

Background and Aims: Numerous studies have suggested that metabolic syndrome (MetS) is related to adrenal incidentaloma (AI) in young adults. Limited data about MetS in geriatric patients diagnosed with AI are available, despite the high incidence of this adrenal disease in the elderly. This study aims to assess the prevalence of MetS and its associated factors in aged patients harboring AI.Patients and Method: We conducted a retrospective, comparative, ...

Introduction: In adults with Addison disease, over glucocorticoid replacement therapy is associated with an increased morbidity and decreased life expectancy, related to low bone mineral density and cardiometabolic outcomes. The aim of our study was to assess the prevalence of carbohydrate metabolism disorders in patients with Addison disease and identify its predictive factors.Patients and methods: A cross sectional study including 50 patients diagnosed...

Introduction: Long-term glucocorticoid replacement therapy in patients with Addison disease has been linked to an increased cardiovascular risk and consequent mortality. Our objective was to determine the frequency of dyslipidemia in patients with Addison disease and its potential predictive factors.Patients and methods: This was a cross-sectional study, performed in the department of endocrinology in Hedi Chaker hospital –Sfax –Tunisia. Fifty ...

Introduction: Inadequate glucocorticoid replacement therapy in Addison disease leads to an increased risk of both cardiovascular disease and metabolic syndrome. The metabolic effects of long-life corticosteroid exposure are due to physiological mechanisms that are associated with carbohydrate metabolism disorder, dyslipidemia and insulin resistance. In this study, we aimed to determine the prevalence and predictive factors of metabolic syndrome in patients with Addison disease...

Background and Aims: Growing scientific evidence supports the hypothesis of an increased cardiometabolic risk in patients harboring adrenal incidentalomas (AI). This risk would be higher in aging populations and patients with functioning adenomas. The current study aims to determine the clinical and biochemical characteristics of metabloic syndrome(MetS) and assess its prevalence in older patients with AI.Patients and Method: We conducted a retrospective...

Background and Aims: Arterial hypertension (AH) is one of the most common comorbidities in the elderly. The association of adrenal incidentaloma (AI) with AH in older patients may influence the clinical and therapeutic outcomes of the latter condition. In the current study, we aimed to assess the prevalence of AH and its clinical and therapeutic features in geriatric patients bearing AI.Patients and Method: We conducted a retrospective descriptive study ...

Introduction: Conventional glucocorticoid replacement therapy has been suggested to increase morbidity in patients with Addison disease and fail to restore their quality of life (QOL). The aim of our study was to assess QOL in patients with Addison disease and to identify factors that determine their QOL.Patients and methods: This cross-sectional study was carried out at the department of Endocrinology in HediChaker hospital-Sfax –Tunisia, from Marc...

Introduction: Patients with Addison disease require lifelong glucocorticoid replacement treatment and it is recommended that glucocortiocoid therapy should be monitored in these patients to avoid over replacement and minimize long-term consequences of bone loss. The present study was carried out with the aim of evaluating bone turnover markers in patients with Addison disease.Patients and methods: A cross sectional study including 50 patients who are fol...

Introduction: Because of a long-term glucocorticoid replacement over many years, patients with Addison disease may have an increased occurrence of osteoporosis. Furthermore, the prevalence of osteoporosis in patients with Addison disease may also be increased because of premature menopause associated autoimmune endocrinopathies and hypovitaminosis D.The objective of this study is to assess the incidence and risk factors for osteoporosis among patients with Addison disease....

Introduction: Hypoparathyroidism (HPT) is an often under-diagnosed condition. It is imperative to diagnose it at an early stage and to initiate prompt treatment given the evolving potential of the disease.The aim of our study is to describe the epidemiological, clinical and paraclinical features of HPT.Patients and Methods: This is a retrospective study of 61 observations of HPT collected at the endocrinology department during a 12-year period.<p cla...